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Hormone Therapies: Newest Advance in Pain Care

Severe, uncontrolled pain may exhaust the adrenal gland, resulting in low levels of pregnenolone and cortisol. While adequate pain control will usually normalize serum hormone levels, opioid-induced suppression of the system may require additional treatment.
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A profound result of recurrent, episodic pain flares is that excess cortisol enters the blood to give a “pseudo” Cushing’s syndrome. Serious side effects may result, including hypertension, hyperlipidemia, diabetes, osteoporosis, and brain tissue atrophy with loss of mental and intellectual powers. Patients with severe, chronic pain should therefore be periodically screened for cortisol excess and deficiencies. HCG is an intriguing compound that contains FSH, LH, and TSH. It also has an anabolic, tissue-building component. HCG’s labeled indication is hypogonadism, and its early clinical use indicates that it may have considerable merit as an adjunct to pain treatment. It may neutralize opioid suppression of testosterone as well as produce its own anabolic growth effects on nerve tissue.

Last updated on: September 6, 2011
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