All Understanding Pain Articles

An estimated 100,000 Americans have sickle cell disease, an inhertied condition that shortens the life cycle—and deforms the shape—of normal red blood cells. Severe pain results as the body struggles to replace them.

During a crisis, people who have sickle cell disease experience severe pain as the body struggles to replace mutated red blood cells with healthy, new ones. Read this patient's account of life with unpredictable pain.

What Is It? Why Do We Have Pain?

Pain is divided into acute pain and chronic pain. Learn how pain signals are transported to the brain through the nervous system, and what happens when nerves are damaged.
There are different types of chronic pain, including neuropathic pain (pain caused by your nerves) and nociceptive pain (pain caused by something besides your nerves). Understand the different in types of chronic (or intractable) pain.