Dextrose Injection Shows Efficacy in Sacroiliac Joint Pain

Sacroiliac joint denervation with hypertonic dextrose injections showed efficacy in 12 of 15 patients (80%) included in a recent study, reported Pankaj Satija, MD, fellow, Department of Anesthesiology, University of Texas Health Science Center at San Antonio, in San Antonio, TX, and colleagues.1

The patients underwent fluoroscopic-guided injections with 16.6% hypertonic dextrose, which is believed to have chemoneuromodulatory and possibly neurolytic effects. As noted, 12 patients experienced a ≥50% decreased in visual analog scale (VAS) score, two patients had a <50% response, and one patient’s pain worsened. The average VAS score decreased from 6.4 at baseline to 1.2 after treatment (P< 0.0001), and pain relief lasted an average of 8.8 months in responders. Responders showed significant pain relief on day 1. No complications were reported.

Reference

  1. Satija P, Parker M, Eckmann M, Ramamurthy S. Dextrose injection of sacral lateral branches for chronic sacroiliac joint pain. Pain. 2011. doi:10.1016/j.jpain.2011.02.282.
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